27 March 2011

The levels of five amino acids in the blood could predict diabetes risk 10 yrs before first symptoms appear.

LONDON: Researchers from the Massachusetts General Hospital (MGH) have suggested that measuring the levels of small molecules in the blood could predict diabetes risk as much as a decade before first symptoms appear.
They said the levels of five amino acids not only indicated increased diabetes risk in a general population but also could differentiate, among individuals with traditional risk factors such as obesity, those most likely to actually develop diabetes.

"These findings raise the possibility that, in selected individuals, these measurements could identify those at highest risk of developing diabetes so that early preventive measures could be instituted," said lead author Thomas Wang.
The researchers found that elevations in five amino acids — isoleucine, leucine, valine, tyrosine and phenylalanine — were significantly associated with the later development of type 2 diabetes.

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